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† Without and with adjustment for BMI. Simple adjusted includes covariates for registry site (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), with and without BMI (18.5 – <25, 25 – <30, ?30kg/m 2 ).
‡ Fully adjusted model includes covariates for registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), BMI (18.5 – <25, 25 – <30, ?30kg/m 2 ), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded.
§ P worthy of of Wald figure to evaluate to have an overall impact away from categorical BI-RADS thickness. All of the mathematical screening had been two-sided.
In the event BI-RADS occurrence failed to tailor threat of breast cancer demise when you look at the link to other pathological issues, female that have BI-RADS step one occurrence had a tendency to feel the large chance, in every stratum
¶ AJCC stage is included just like the a categorical covariate within the models which have all of the degree combined, which have and you will as opposed to phase IV.
Emergency design results for the family ranging from mammographic thickness and chance from cancer of the breast dying, complete and by AJCC phase*
* AJCC = American Mutual Committee towards the Malignant tumors; BI-RADS = Breast Imaging fuck marry kill Reporting and you can Data Program; Body mass index = body mass index; CI = believe period; Hour = issues proportion. N = 96 people omitted regarding the cause-particular patterns.
† Without and with adjustment for BMI. Simple adjusted includes covariates for registry site (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), with and without BMI (18.5 – <25, 25 – <30, ?30kg/m 2 ).
‡ Fully adjusted model includes covariates for registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), BMI (18.5 – <25, 25 – <30, ?30kg/m 2 ), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded.
§ P well worth out of Wald figure to test having an overall perception regarding categorical BI-RADS thickness. Every mathematical evaluating have been a couple of-sided.
Regardless of if BI-RADS thickness did not personalize threat of breast cancer demise inside the relationship to most other pathological facts, ladies that have BI-RADS 1 occurrence tended to have the higher chance, in virtually any stratum
¶ AJCC phase is included because the an effective categorical covariate inside designs having all the degrees shared, that have and you will instead phase IV.
Among females that have cancers with a minimum of dos.0cm, BI-RADS step one thickness was associated with the an increased threat of breast cancer tumors passing (Time = step 1.55, 95% CI = step 1.14 to help you dos.09; P = .003 to possess overall effectation of BI-RADS density; Table cuatro). Ladies who had both BI-RADS step 1 density and highest-stages cancers had a greater threat of breast cancer demise (Time = step one.45, 95% CI = step one.05 so you’re able to 2.02; P = .13 for overall aftereffect of density).
Survival design outcomes for the brand new relatives between mammographic occurrence and you may risk regarding breast cancer death, stratified because of the tumor attributes, AJCC values I–IV shared*
* N = 96 women excluded from cause-specific models. Fully adjusted model includes covariates for AJCC stage (I, IIA, IIB, III, IV), registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), body mass index (18.5 – <25, 25 – <30, ?30kg/m 2 ), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded. AJCC = American Joint Committee on Cancer; BI-RADS = Breast Imaging Reporting and Data System; CI = confidence interval; ER = estrogen receptor; HR = hazard ratio; PR = progesterone receptor.